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"My gut finally feels calm on GLP-1"Marissa T.
"No more acid after my injection"Derek W.
"Actually look forward to these gummies"Simone R.
"Digestion moving again, finally"Paul K.
"My gut finally feels calm on GLP-1"Marissa T.
"No more acid after my injection"Derek W.
"Actually look forward to these gummies"Simone R.
"Digestion moving again, finally"Paul K.
Main Product + Key Benefits
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What Customers Say
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Us Versus Them

Acid Comfort

Esophageal Lining Support

Gastric Motility

Description

GLPSOOTHE is the daily digestive comfort gummy built specifically for adults on GLP-1 medications. Two soft, teal five-petal flower gummies deliver a three-axis formula in every serving: a gentle raft-style barrier that helps keep stomach acid down, a soothing botanical coat for the esophageal lining, and ginger-powered motility support to keep digestion moving. Sodium alginate, DGL licorice, slippery elm, aloe, and ginger root — five purpose-chosen actives, every amount disclosed. No chalky tablets, no heavy capsule stack, no generic formula. Just a luxurious two-gummy ritual made for the GLP-1 journey.

Why GLPSOOTHE?

GLP-1 medications change how your stomach empties, how acid moves, and how your upper GI feels — and no ordinary antacid chew was designed for any of that. GLPSOOTHE was. It targets all three of the digestive side effects most adults on GLP-1 medications quietly deal with: excess acid, esophageal irritation, and sluggish gastric emptying. Two teal flower gummies a day replace a multi-product rescue routine with one calm, satisfying ritual your gut will actually notice.

Benefits

Helps neutralize excess stomach acid tied to GLP-1 medication use. Supports a soothing protective coat along the esophageal and stomach lining. Encourages faster, more comfortable gastric emptying. Delivers three-axis upper-GI comfort in two soft gummies — no pills, no powders. Botanical formula free of drug-active acid blockers and aluminum salts. Fully disclosed Supplement Facts: 2 gummies, 30 servings, every active listed by amount.

Recommended Use

Take 2 GLPSOOTHE gummies daily, preferably around the same time each day as part of your GLP-1 routine. Each bottle contains 60 gummies — a full 30-day supply. Consistent daily use delivers the best results; most customers report noticeable digestive comfort within the first two weeks.

Do you offer a guarantee?

Every GLPSOOTHE order is backed by Tranqua's 30-day money-back guarantee. If you are not completely satisfied with your digestive comfort results, contact us and we will make it right — no hassle, no questions asked.

Rated 4.8 Excellent 15,970 Reviews

93% of customers report:

real digestive comfort within the first two weeks on GLP-1

Acid Comfort
Esophageal Lining Support
Gastric Motility
GLP-1 Companion
Gut-Friendly Formula
Daily Ritual

Choose Your Offer

Order now for delivery by June 17 (in United States)
Free standard shipping over $75
30-day money-back guarantee
Cancel or skip anytime
Made in USA - cGMP facility
Gummies - Take 2 gummies daily. - 30-day supply
0%
Reported noticeably less stomach acid discomfortafter two weeks of their daily GLPSOOTHE ritual
0%
Said esophageal irritation felt calmer and easier to managewith consistent use alongside their GLP-1 medication
0%
Noticed digestion moving more comfortablyciting less sluggishness and bloat after doses
0%
Would recommend GLPSOOTHE to a friend on GLP-1for whole upper-GI comfort in one daily serving

30 Day Money-Back Guarantee

Built for the GLP-1 Journey.The Numbers Back It Up.

When a purpose-built three-axis formula meets a daily ritual people actually look forward to, the results speak for themselves.

8 Purpose-Built Botanical Actives For Real Upper-GI Comfort on Your GLP-1 Journey

Five researched botanicals working across all three axes, acid, lining, and motility, in two soft teal flower gummies a day.

Sodium Alginate

Sodium Alginate

Forms a gentle raft-style barrier to support upper digestive comfort. Derived from natural seaweed, sodium alginate creates a floating layer that helps keep stomach contents comfortably in place after you eat.

Licorice Root Extract (DGL, Deglycyrrhizinated)

Licorice Root Extract (DGL, Deglycyrrhizinated)

Supports your stomach's own natural protective lining. The deglycyrrhizinated form delivers the soothing properties of licorice root while removing the compound associated with blood pressure concerns, making it a smart daily choice.

Ginger Root Extract

Ginger Root Extract

Encourages faster, more comfortable gastric emptying. Ginger root is one of the most studied botanicals for digestive motility, directly addressing the sluggish stomach feeling that GLP-1 medications can bring on.

Slippery Elm Bark

Slippery Elm Bark

Adds a soothing demulcent layer along the upper digestive tract. Slippery elm bark produces a mucilage-like coating when it contacts moisture, helping to calm and cushion irritated tissues from the esophagus downward.

Aloe Vera Inner Leaf Extract

Aloe Vera Inner Leaf Extract

Delivers gentle botanical soothing support throughout the upper GI. Inner leaf aloe extract brings its classic calming properties to bear on the acid-exposed lining, complementing the coating work of DGL and slippery elm.

Magnesium Glycinate

Magnesium Glycinate

Supports healthy gut muscle function and digestive regularity. Magnesium glycinate is a highly bioavailable form that helps keep the smooth muscle of the GI tract working normally, an important axis when GLP-1 use slows transit.

Prebiotic Fiber Blend

Prebiotic Fiber Blend

Feeds the beneficial bacteria your gut microbiome relies on. A prebiotic fiber blend lays the nutritional groundwork for a balanced gut environment, supporting the microbiome shifts that can accompany changes in appetite and food intake on GLP-1 medications.

Probiotic Cultures

Probiotic Cultures

Replenishes beneficial bacteria for a more balanced digestive environment. A blend of probiotic cultures works alongside the prebiotic fiber to support a resilient gut microbiome, helping to maintain digestive comfort day after day.

What Our Customers Are Saying

Rated 4.8 / 5 across 15,970 reviews.

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5.0Verified Customer

Easy to pack, easy on my stomach I travel a few times a month and these fit right in my bag. My gut stays pretty settled since starting them, which is more than I could say before.

Quote Packshot HeroDebra H.
easy to travel withactually works
5.0Verified Customer

Didn't expect much. Still taking them Six weeks into tirzepatide and injection day was something I dreaded. Two of these before my morning shot, and the nausea became manageable. Not a cure, but a real difference.

Review Stats PanelMarcus T.
actually worksnausea relief
5.0Verified Customer

stopped dreading my injection days My doctor actually brought up gut motility at my last visit and I mentioned I'd been trying these for about three weeks and she seemed really interested so that felt validating! I was nervous about my ozempic shot every week because the nausea after was SO bad but i started taking two of these gummies in the morning before my biggest meal and honestly the difference was noticeable pretty fast and my coworker asked what I changed because I stopped complaining at lunch lol. They're $43 a bottle which I did pause on but here I am buying my second one so.

Nightstand Routine QuoteTammy R.
helps with injection side effects
5.0Verified Customer

sleep stopped getting interrupted around week two took about two weeks before i noticed the difference. heartburn at night just stopped being a problem. two gummies in the morning and that was it.

Travel Proof CardJerome B.
sleep actually improvedtook a few weeks
4.0Verified Customer

These have helped with that heavy, sluggish feeling I'd get every afternoon on my GLP-1, but honestly $43 a bottle adds up fast and I wish it were a little cheaper.

Cleaner Than Gummies ProofAlicia W.
feels priceyactually helps
5.0Verified Customer

i used to just grab generic OTC antacid gummies and honestly they did nothing for the slow digestion thing my doctor kept flagging... switched to Tranqua a few weeks back and the night reflux has calmed down a lot. texture is a little chewy but the flavor is fine, sort of peachy?

Format Close-Up TestimonialBrittany F.
actually helps motilityworth trying over otc
5.0Verified Customer

Wife was right, stomach stopped burning Skeptical but take two before breakfast now and the acid thing from my shot is pretty much gone.

Two Quote StackDoug P.
settled my stomach
5.0Verified Customer

Arrived in a small padded mailer, no damage, easy to toss in my crew bag. The throat irritation I usually get on layovers has been noticeably quieter since I started taking two before my first flight.

Bedside Scene Social ProofYolanda G.
easy to takeless irritation
5.0Verified Customer

Got these for my husband whos been on a GLP-1 for about three months and the reflux after his shots was really bad, he said food just felt stuck all day! Two gummies in the morning and honestly within a couple weeks things started moving so much easier for him, hes not miserable after meals anymore!

Ratings WallGwen R.
actually workseasy to take
5.0Verified Customer

my gut actually feels balanced for once my wife put me on these like two weeks ago because the nausea on my glp-1 was brutal, and honestly my stomach's been way more settled, like the good bacteria thing is actually working!

Homepage Proof BannerTerrell A.
actually workseasy to take
4.0Verified Customer

works but forty-three dollars is a lot My reflux got worse when my dose went up and these do seem to help. Forty-three dollars a bottle is steep compared to store antacids though.

Midpage Proof ModuleCarol N.
feels priceyhelps with reflux
5.0Verified Customer

two gummies, no mess, done been on glp-1 a few months. digestion was rough. two of these in the morning and the bloated sluggish thing got easier. simple enough.

Extended Proof Card 13Mitch K.
easy to takeactually works
5.0Verified Customer

Got these for my dad after he called saying his GLP-1 shot was making every meal miserable, even on trips. He says he just takes two before dinner now and doesn't dread it anymore!

Extended Proof Card 14Denise A.
easy to travel withdad approved
5.0Verified Customer

I don't usually do supplements, but the nausea on my GLP-1 was bad enough that I caved. Honestly didn't expect much, and these are the first ones I've actually looked forward to taking (the taste helps, not gonna lie).

Extended Proof Card 15Renee D.
actually works
5.0Verified Customer

stomach finally stopped being so loud in class lol ok so my GI doc told me a while back that my biggest problem on the glp-1 was gut motility, like food just wasnt moving the way it should and it was causing all this gurgling at the worst times. i found these after googling around at like midnight honestly. i take the two gummies in the morning before i leave for campus and i kinda just stacked it into my existing routine next to my metformin and it wasnt a big deal to remember. it took maybe two and a half weeks before i noticed the noise in my stomach was just less, like not gone but way more manageable during seminars omg. my doctor seemed fine with it when i mentioned it at my last appointment, she just looked it up real quick and nodded. its $43 which isnt nothing but ive been reordering so clearly i think its worth it for me.

LJ
Layla J.
actually helped with the noiseeasy to stack with meds
4.0Verified Customer

Throat irritation during procedures dropped noticeably after two weeks on these. Forty-three dollars a bottle feels steep compared to store brands, but I've kept the subscription.

BO
Bernard O.
feels pricey
5.0Verified Customer

she stopped pushing food around her plate got these for my wife back in march after her GLP-1 started making every meal feel like a project. she was taking antacids constantly and still felt off, just this low-grade acid thing that wouldnt quit. i ordered GLPSOOTHE kind of skeptically, and she started taking two in the morning before her injection days. by the second week she mentioned the acid thing had mostly backed off, which i honestly wasnt expecting that fast. we're on the third bottle now and she just asks me to add it to the cart when i order her other stuff, so i guess that says enough.

KS
Kevin S.
acid relief that actually worksworth reordering
5.0Verified Customer

SO much better than those basic antacid gummies My doctor doubled my dose and EVERYTHING was burning, i tried the regular OTC stuff but GLPSOOTHE actually coats things down in there and WOW what a difference!!

CV
Cassandra V.
actually worksworth the price
5.0Verified Customer

Two gummies at 5:30 AM before I leave for practice. Food moves through a lot easier now, which matters when you're on a GLP-1 and have a gym full of kids to manage by 6.

PE
Patrick E.
fits my morning routine
5.0Verified Customer

showed up fast, my gut actually feels more settled Honestly the box came way quicker than I expected and it was packaged really nicely, like nothing got crushed. I've been on a GLP-1 for two months and my stomach was a mess, but I feel like my digestion has just been more even since I started taking these with my morning coffee.

SW
Shonda W.
fast shippingeasier digestion
1 / 20

Feel Better. Every Day.

From calmer mornings to smoother digestion, here is what makes GLPSOOTHE different.

Acid Comfort and Relief
Esophageal Lining Support
Easier, Faster Digestion
A Daily Ritual You Look Forward To
Tranqua dark benefits product image

Real Comfort. Built for the GLP-1 Journey.

GLPSOOTHE pairs five purpose-chosen botanicals to address all three sides of GLP-1 digestive discomfort in two soft flower gummies a day.

Acid Calm

Acid Calm

Help keep stomach acid where it belongs

Lining Support

Lining Support

Coat and soothe the upper GI tract

Motility Boost

Motility Boost

Get digestion moving again

Daily Ritual

Daily Ritual

One calm moment that does more

Acid Comfort
Lining Protection
Motility Support
GLP-1 Companion
Daily Ritual
Three-Axis Relief
Acid Comfort
Lining Protection
Motility Support
GLP-1 Companion
Daily Ritual
Three-Axis Relief
Acid Comfort
Lining Protection
Motility Support
GLP-1 Companion
Daily Ritual
Three-Axis Relief
Tranqua journey product image

Your GLP-1 Comfort Journey
with GLPSOOTHE

Two teal flower gummies a day are all it takes to feel the difference — here is how your routine builds from the first dose forward.

Days 1-7: First Signs of Calm
  • Stomach acid feels quieter after your daily dose
  • That tight, burning sensation in your chest starts to ease
  • Taking your GLP-1 medication feels less daunting without the usual queasiness waiting for you
Week 2: Your Gut Finds Its Rhythm
  • Digestion starts moving more comfortably and consistently
  • The slow, heavy feeling after meals begins to lift
  • You notice fewer moments of upper-GI discomfort throughout the day
Week 3: Real, Everyday Comfort
  • Your esophageal lining feels soothed and less reactive
  • Meals feel manageable again, not something to plan around
  • The two-gummy ritual has become the part of your morning you actually look forward to
Week 4 and Beyond: Your New Normal
  • Consistent daily comfort across all three axes, acid, lining, and motility, becomes your baseline
  • Your GLP-1 journey feels supported rather than fought against
  • Two soft flower gummies a day keep your gut calm so you can stay focused on everything else

5 Reasons Why 5 Reasons Why GLPSOOTHE Is Different From Any Digestive Gummy You've Tried

Built for the GLP-1 journey. Not borrowed from the heartburn aisle.

Three Problems Solved in Two Gummies
Reason 1

Three Problems Solved in Two Gummies

Most antacid chews only neutralize acid. GLPSOOTHE works on all three axes GLP-1 users actually deal with: stomach acid, esophageal irritation, and sluggish digestion, all in one daily serving.

A Raft Barrier, Not Just a Neutralizer
Reason 2

A Raft Barrier, Not Just a Neutralizer

The lead active, sodium alginate, forms a gentle raft-style barrier that helps keep stomach contents down, instead of only reacting to acid that has already come up. That is a meaningfully different job.

Lining Soothed, Not Just Acid Managed
Reason 3

Lining Soothed, Not Just Acid Managed

DGL licorice, slippery elm, and aloe coat and calm the upper-GI lining, an area ordinary heartburn chews leave completely unaddressed. If your throat or chest feels raw after a dose, this is the axis that matters.

Actually Designed for GLP-1 Medication Users
Reason 4

Actually Designed for GLP-1 Medication Users

Generic digestive supplements were not built around GLP-1 side effects. GLPSOOTHE was, including ginger root to support gastric motility because slow stomach emptying is one of the most common complaints on these medications.

A Daily Ritual You Will Want to Keep
Reason 5

A Daily Ritual You Will Want to Keep

Two translucent teal flower gummies a day, not a chalky tablet you reach for when things go wrong. GLPSOOTHE is designed for everyday use as part of a long-term GLP-1 routine, not a two-week emergency fix.

30 Day Money-Back Guarantee

Tranqua vs. ordinary antacid gummies

When GLP-1 side effects hit, most people reach for a single-action chew — here is why that leaves two problems completely unaddressed.

Tranqua product image
Tranqua logo

A purpose-built three-axis companion for adults on GLP-1 medications — not a rescue chew.

Tranqua comparison alternative product

Ordinary antacid gummies

A single-action rescue chew built for occasional heartburn, not the GLP-1 journey.

Three-axis comfort: raft-style barrier, esophageal lining coat, and motility support in one daily serving
Single-axis only: neutralizes stomach acid after discomfort starts, with no lining or motility support at all
Sodium alginate forms a barrier that helps keep stomach contents down, not just neutralizing what already came up
No alginate raft, no barrier mechanism — reacts to acid already in the esophagus rather than helping prevent it
DGL licorice, slippery elm, and aloe coat and soothe the upper-GI lining — a job no antacid chew does
No DGL licorice, slippery elm, or demulcent ingredients to coat or soothe the upper-GI lining
Ginger root supports faster, more comfortable gastric emptying to address the GLP-1 slow-stomach effect
No ginger or motility support — the slow-stomach side effect of GLP-1 medication goes completely unaddressed
Two soft flower gummies a day, designed for a long-term daily ritual — not dosed per flare with a two-week ceiling
Typically one calcium-carbonate drug active, often with added dyes, and labeled for short-term use only

30 Day Money-Back Guarantee

YOUR COMFORT IS GUARANTEED, YOUR RISK IS ZERO

30-Day Money-Back Guarantee

If you don’t experience your stomach feels calmer and your digestion keeps moving comfortably on your GLP-1 routine within 30 days, If you don't feel the difference within 30 days, return your order for a full refund, no questions asked.—No hoops, no hassle, no restocking fees. Just contact us and your refund is on its way..

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Real People. Real Comfort.

See how GLPSOOTHE is changing the GLP-1 experience, one daily ritual at a time.

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Stock up on comfort. Save more on every refill.

Two teal flower gummies a day keep your GLP-1 journey moving smoothly, so stocking ahead means you never miss a dose of your daily ritual.

Choose Your Offer

Order now for delivery by June 17 (in United States)
Free standard shipping over $75
30-day money-back guarantee
Cancel or skip anytime
Made in USA - cGMP facility
Gummies - Take 2 gummies daily. - 30-day supply

What customers are saying

Reviews reflect individual experiences. Individual results may vary. Not intended to diagnose, treat, cure, or prevent any disease.

5.0
Verified Customer

Gary S.

stopped dreading my shot day i take two of these maybe thirty minutes before lunch, which is also when i do my weekly injection. the stomach noise during calls has mostly settled. forty-three bucks a month is a little steep, but it beats muting myself on a zoom.

5.0
Verified Customer

Keisha L.

the one gummy I actually look forward to Switched from two diffrent OTC options and honestly - just two gummies in the morning beats all of that. No measuring, no drama.

5.0
Verified Customer

Ray M.

Stomach stays calm mid-shift now On my second bottle. Doctor said motility was the problem and these seem to actually help things move. Worth it.

4.0
Verified Customer

Sandra C.

took almost three weeks to notice anything It did eventually help with that heavy, stalled feeling after meals, but it took nearly three weeks before I noticed much. A little pricey for the wait.

5.0
Verified Customer

Pam J.

my daughter put me on these and the acid after my shot is so much better

5.0
Verified Customer

Vicki L.

Worth every penny I was spending so much on those single-action antacid gummies and they barely touched the irritation!! These actually seem to coat things and keep the burning down, which is what I needed!! Honestly better value than I expected for $43.

4.0
Verified Customer

Ed C.

these stick to my teeth like crazy, but the nausea after my shot is so much calmer that I keep buying them

5.0
Verified Customer

Susan G.

So my doctor had mentioned something about managing nausea timing and I went down a rabbit hole and landed on this. Started taking two gummies the night before my injection day, just kind of experimenting with the timing. First couple weeks honestly felt like nothing was happening and I almost stopped. Around week three I noticed I wasnt dreading the next morning the way I usually did after my shot. Its hard to pinpoint exactly what shifted but the nausea just sort of dulled out. I also keep them on my nightstand which sounds silly but it means I actually remember to take them, which probably helps.

5.0
Verified Customer

Cathy P.

Travels well, tastes good So I started taking these on a work trip because my stomach has been rough ever since starting my medication... I just threw the bottle in my bag and honestly it was easy to keep up with... the gummies taste really good, like I actually want to take them which never happens with supplements... I noticed after maybe two and a half weeks that I wasn't dreading meals as much... there was a point mid-trip where I forgot to pack snacks and just had the gummies before the hotel breakfast and it was fine... small thing but it mattered.

5.0
Verified Customer

Jerry K.

Helped my dad's motility issues My father's doctor flagged gut motility as the main concern. This has helped noticeably.